Thrush Research Today is a free monthly online journal that collates and summarizes the latest research about Thrush, including details on oral, vaginal, symptoms, prevention, treatment, infection.

Interventions for preventing oral mucositis for patients with cancer receiving treatment.

Worthington HV, Clarkson JE, Bryan G, Furness S, Glenny AM, Littlewood A, McCabe MG, Meyer S, Khalid T

Cochrane Oral Health Group, School of Dentistry, The University of Manchester, Coupland III Building, Oxford Road, Manchester, UK, M13 9PL.

Published 14 April 2011 in Cochrane Database Syst Rev, 4: CD000978.
Full-text of this article is available online (may require subscription).

Articles on Thrush published 11 November 2010:

Interventions for the prevention and management of oropharyngeal candidiasis associated with HIV infection in adults and children.   Cochrane Database Syst Rev, 11: CD003940.

[Abstract] [Full-text]

Articles on Thrush published 24 August 2010:

Genetic variation of innate immune genes in HIV-infected african patients with or without oropharyngeal candidiasis.   J Acquir Immune Defic Syndr, 55(1): 87-94.

BACKGROUND: The occurrence of oropharyngeal candidiasis (OPC) in combination with HIV disease progression is a very common phenomenon. However, not all HIV-infected patients develop OPC, even when they progress to low CD4 T-cell counts. Because T-cell immunity is defective in AIDS, the innate defence mechanisms are likely to have a central role in antifungal immunity in these patients. We investigated whether genetic variations in the innate immune genes DECTIN-1, TLR2, TLR4, TIRAP, and ... [Abstract] [Full-text]

Articles on Thrush published 18 August 2010:

Development and validation of an in vivo Candida albicans biofilm denture model.   Infect Immun, 78(9): 3650-9.

The most common form of oral candidiasis, denture-associated stomatitis, involves biofilm growth on an oral prosthetic surface. Cells in this unique environment are equipped to withstand host defenses and survive antifungal therapy. Studies of the biofilm process on dentures have primarily been limited to in vitro models. We developed a rodent acrylic denture model and characterized the Candida albicans and mixed oral bacterial flora biofilm formation, architecture, and drug resistance in vivo, ... [Abstract] [Full-text]

Articles on Thrush published 21 July 2010:

Oral candidiasis in patients receiving radiation therapy for head and neck cancer.   Otolaryngol Head Neck Surg, 143(2): 242-7.

OBJECTIVE: To investigate oral candidiasis in patients with head and neck cancer before, during, and after radiation therapy, and to explore its association with clinical oropharyngeal symptoms. STUDY DESIGN: A cohort study. SETTING: University hospital. SUBJECTS AND METHODS: Subjects who received radiation therapy (RT) for the treatment of head and neck cancer were divided into two groups: an oral cavity irradiated group (OIRR group, n = 29) and an oral cavity nonirradiated group (ONIRR group, ... [Abstract] [Full-text]

Articles on Thrush published 8 July 2010:

Interventions for treating oral candidiasis for patients with cancer receiving treatment.   Cochrane Database Syst Rev, 7: CD001972.

BACKGROUND: Treatment of cancer is increasingly effective but is associated with short and long term side effects. Oral and gastrointestinal side effects, including oral candidiasis, remain a major source of illness despite the use of a variety of agents to treat them. OBJECTIVES: To assess the effectiveness of interventions for the treatment of oral candidiasis for patients with cancer receiving chemotherapy or radiotherapy or both. SEARCH STRATEGY: Computerised searches of Cochrane Oral ... [Abstract] [Full-text]

Articles on Thrush published 25 August 2009:

Effect of amine fluoride-stannous fluoride preparations on oral yeasts in the elderly: a randomised placebo-controlled trial.   Gerodontology, 26(3): 202-9.

OBJECTIVES: Oral yeast infections are an emerging problem among medically compromised and frail elderly. Antifungal drug resistance is also increasing because of an increase in non-albicans Candida strains in these populations. We therefore set out to study, in the randomised-controlled trial setting if the use of a topical amine fluoride-stannous fluoride combination (AmF-SnF2) could control oral Candida growth in the elderly. The hypothesis was based on earlier findings showing that in vitro ... [Abstract] [Full-text]

Articles on Thrush published 10 June 2009:

Chronic tongue ulceration resolved by sulpiride: a report of two cases.   Clin Exp Dermatol, 34(5): e40-2.

We report two patients with chronic tongue ulceration who were successfully treated using sulpiride. The clinical diagnosis was oral candidiasis related to long-term steroid treatment. The results of the culture test and cytological examination supported this diagnosis, but antifungal treatment was ineffective and the tongue pain in these patients became more severe. Furthermore, the pain could not be relieved by nonsteroidal anti-inflammatory drugs (NSAIDs). We therefore prescribed sulpiride ... [Abstract] [Full-text]

Articles on Thrush published 19 February 2009:

Carriage rate and virulence attributes of oral Candida albicans isolates from patients with oral lichen planus: a study in an ethnic Chinese cohort.   Mycoses, 52(2): 161-5.

The objectives of this study are to investigate the carriage rate of Candida albicans from the patients with oral lichen planus (OLP, erosive and non-erosive subtypes) and the healthy control individuals in a Chinese cohort and then to compare the virulence attributes of these isolates. Oral C. albicans isolates from 300 patients with OLP as well as 128 healthy controls were isolated and a total of 112 isolates from patients with erosive OLP (62), non-erosive OLP (24) and healthy control (26) ... [Abstract] [Full-text]

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